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Pyridoxine Hydrochloride (Vitamin B6)

Drug Class: Vitamins and Minerals
Dosage Form: Tablet
Strength: 50 mg
Indications/Special comments: For prevention and treatment of pyridoxine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used as antidote in cyclosporin poisoning and to terminate seizures and prevent neuropathy associated with isoniazid poisoning.
Dosage Administration: Adult: Deficiency states: Oral: 20 - 50mg up to 3 times daily. Isoniazid neuropathy, prophylaxis: 10mg daily, therapeutic - 50mg three times daily. Idiopathic sideroblastic anaemia: Oral: 100 - 400mg daily in divided doses. Nutritional supplement - Dietary supplement: Oral: 10 - 20mg per day for three weeks followed by 2 to 5mg per day (in a multivitamin preparation) for several weeks. Drug Induced deficiency: Prevention: Oral: 10 -50mg per day for penicillamine or 100 - 300mg per day for cycloserine, hydralazine, or isoniazid. Treatment: Oral: 50 to 100mg per day as needed to prevent relapse; IM or IV: 50 to 200mg per day for three weeks, followed by 25 to 100mg per day as needed. Child: Dietary supplement: Oral: 2.5 to 10mg per day for three weeks, followed by 2 to 5mg per day (in a multivitamin preparation) for several weeks.