Pantoprazole

Drug Class: Gastrointestinal System Agents
Dosage Form: Capsule
Strength: 40mg
Indications/Special comments: Helicobacter pylori eradication in combination with amoxicillin and clarithromycin; or in combination with clarithromycin and metronidazole. Benign gastric ulcer. Duodenal ulcer. Prophylaxis of NSAID-associated gastric ulcer in patients with an increased risk of gastroduodenal complications that require continued NSAID treatment. Prophylaxis of NSAID-associated duodenal ulcer in patients with an increased risk of gastroduodenal complications that require continued NSAID treatment. Gastro-oesophageal reflux disease. Zollinger–Ellison syndrome (and other hypersecretory conditions.
Dosage Administration: Helicobacter pylori eradication in combination with amoxicillin and clarithromycin; or in combination with clarithromycin and metronidazole - Oral: Adult: 40mg twice daily. Benign gastric ulcer: Oral: Adult: 40mg daily for 8 weeks; increased if necessary up to 80mg daily, dose increased in severe cases. Gastric ulcer/Duodenal ulcer: Oral: Adult:40mg daily for 4 weeks; increased if necessary up to 80mg daily, dose increased in severe cases. Prophylaxis of NSAID-associated duodenal ulcer in patients with an increased risk of gastroduodenal complications that require continued NSAID treatment. Oral: Adult: 20mg daily. Gastro-oesophageal reflux disease. Oral: Adult: 20 – 80mg daily for 4 weeks, continued for further 4 weeks if not fully healed, dose to be taken in the morning; maintenance 20mg daily and increased to 40mg daily, increased only if symptoms return. Zollinger–Ellison Syndrome (and other hypersecretory conditions). Oral: Adult: Initially, 80mg daily (max. per dose 80mg), adjusted according to response. Elderly: 40mg daily.Oral: initially 80mg, alternatively 160mg in 2 divided doses, if rapid acid control required, then 80mg once daily (max. per dose 80mg), adjusted according to response.