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Vitamins and Minerals, Zinc Sulphate
Dosage form:
Injection
Strength:
1mg/ml
Indications/Special comments:
Zinc deficiency or supplementation in zinc-losing conditions. Additional elemental zinc for intravenous nutrition
Dosage Administration:
By intravenous injection: Adult: 6.5mg daily (Zn2+ 100 micromol).
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Vitamins and Minerals, Vitamin B Complex
Dosage form:
Injection
Strength:
n/a
Indications/Special comments:
In disorders requiring parenteral administration of vitamins, i.e. pre- and post-operative treatment, when requirements are increased as in fever, severe burns, increased metabolism, pregnancy, gastrointestinal disorders interfering with intake or absorption of vitamins, prolonged or wasting diseases, alcoholism and where other deficiencies exist.
Dosage Administration:
Usually 0.25 to 2mL by intramuscular or slow intravenous injection. High concentrations given intravenously may be diluted using parenteral infusion solutions.
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Vitamins and Minerals, Vitamin A
Dosage form:
Injection
Strength:
50,000 IU/ml
Indications/Special comments:
For prevention or treatment of vitamin A deficiency states, causing keratomalacia, xerophthalmia and nyctalopia (night blindness). This may occur as a result of inadequate nutrition or intestinal malabsorption.
Dosage Administration:
Adult: Deficiency: IM, Intravenous infusion, as a part of total parenteral nutrition solution, the specific amount determined by individual patient need. - IM: 15,000 to 30,000 RE (50,000 - 100,000 units) a day for three days, followed by 15,000 RE (50,000 units) a day for two weeks. Child: Deficiency: Infants less than 1year: IM: 1500 - 3000 RE (500 - 10,000 units) a day for ten days; In severe deficiency: IM: 2250 to 4500 RE (7500 to 15,000 units) a day for ten days. Children 1 - 8 years of age: IM: 1500 - 4500 RE (5000 - 15,000 units) a day for ten days; In severe deficiency: IM: 5250 to 10,500 RE (17,500 - 35,000 units) a day for ten days.
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Vitamins and Minerals, Thiamine Hydrochloride (Vitamin B1)
Dosage form:
Tablet
Strength:
100mg
Indications/Special comments:
For prevention and treatment of thiamine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is used for temporary metabolic correction of genetic enzyme deficiency diseases such as subacute nercotizing encephalomyelopathy (SNE, Leigh’s disease), maple syrup urine disease (branched-chain aminoacidopathy), and lactic acidosis associated with pyruvate carboxylase deficiency and hyperalaninemia.
Dosage Administration:
Adult: Nutritional supplement (Vitamin) Beriberi (initial in mild or maintenance following severe): 5 to 10mg three times a day (in a multivitamin preparation). Beriberi (critical illness): IM or slow IV: 5 - 100mg three times a day followed by maintenance oral administration. Treatment of deficiency: 1 - 10mg three times a day until improvement occurs, followed by recommended dietary allowance. Child: Nutritional supplement (Vitamin) Beriberi (mild): Infants: 10mg per day. Beriberi (critical illness): Treatment of deficiency: Oral: 10 to 50mg per day in divided doses. Dietary supplement: Infants: Oral: 300 to 500mcg (0.3 - 0.5mg) per day. Child: Oral: 500mcg (0.5mg) to 1mg per day.
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Vitamins and Minerals, Thiamine Hydrochloride (Vitamin B1)
Dosage form:
Injection
Strength:
100mg/ml
Indications/Special comments:
For prevention and treatment of thiamine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is used for temporary metabolic correction of genetic enzyme deficiency diseases such as subacute nercotizing encephalomyelopathy (SNE, Leigh’s disease), maple syrup urine disease (branched-chain aminoacidopathy), and lactic acidosis associated with pyruvate carboxylase deficiency and hyperalaninemia.
Dosage Administration:
Adult: Beriberi (critical illness): IM or slow IV: 5 - 100mg three times a day followed by maintenance oral administration. Infants: IM or slow IV: 10 - 25mg per day.
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Vitamins and Minerals, Sodium Phosphate
Dosage form:
Tablet
Strength:
Tablet (monobasic & dibasic): 1.5g
Indications/Special comments:
Treatment and prevention of hypophosphatemia
Dosage Administration:
See package insert
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Vitamins and Minerals, Selenium
Dosage form:
Injection
Strength:
40mcg/ml
Indications/Special comments:
Selenium Injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration of selenium in TPN solutions helps to maintain plasma selenium levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Dosage Administration:
Selenium deficiency: By intramuscular injection, or by intravenous injection: Adult 100 – 500 micrograms daily.
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Vitamins and Minerals, Pyridoxine Hydrochloride (Vitamin B6)
Dosage form:
Tablet
Strength:
50 mg
Indications/Special comments:
For prevention and treatment of pyridoxine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used as antidote in cyclosporin poisoning and to terminate seizures and prevent neuropathy associated with isoniazid poisoning.
Dosage Administration:
Adult: Deficiency states: Oral: 20 - 50mg up to 3 times daily. Isoniazid neuropathy, prophylaxis: 10mg daily, therapeutic - 50mg three times daily. Idiopathic sideroblastic anaemia: Oral: 100 - 400mg daily in divided doses. Nutritional supplement - Dietary supplement: Oral: 10 - 20mg per day for three weeks followed by 2 to 5mg per day (in a multivitamin preparation) for several weeks. Drug Induced deficiency: Prevention: Oral: 10 -50mg per day for penicillamine or 100 - 300mg per day for cycloserine, hydralazine, or isoniazid. Treatment: Oral: 50 to 100mg per day as needed to prevent relapse; IM or IV: 50 to 200mg per day for three weeks, followed by 25 to 100mg per day as needed. Child: Dietary supplement: Oral: 2.5 to 10mg per day for three weeks, followed by 2 to 5mg per day (in a multivitamin preparation) for several weeks.
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Vitamins and Minerals, Pyridoxine Hydrochloride (Vitamin B6)
Dosage form:
Injection
Strength:
25mg/ml in 2ml ampoule, 150mg/ml
Indications/Special comments:
For prevention and treatment of pyridoxine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is also used as antidote in cyclosporin poisoning and to terminate seizures and prevent neuropathy associated with isoniazid poisoning.
Dosage Administration:
Drug induced deficency: IM or IV: 50 to 200mg per day for three weeks, followed by 25 to 100mg per day as needed.
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Vitamins and Minerals, Potassium Phosphate
Dosage form:
Tablet
Strength:
250mg
Indications/Special comments:
For use in patients with elevated urinary pH. Helps keep calcium soluble and reduces odour and rash caused by ammoniacal urine. Also, by acidifying the urine, it increases the antibacterial activity of methenamine mandelate and methenamine hippurate
Dosage Administration:
Two tablets dissolved in 6 - 8oz. of water 4 times daily with meals and at bedtime. For best results, let the tablets soak in water for 2 to 5 minutes, or more if necessary, and stir. If any tablet particles remain undissolved, they may be crushed and stirred vigorously to speed dissolution.
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