• Vitamins and Minerals, Zinc Sulphate
    Dosage form: Injection
    Strength: 1mg/ml
    Indications/Special comments: Zinc deficiency or supplementation in zinc-losing conditions. Additional elemental zinc for intravenous nutrition
    Dosage Administration: By intravenous injection: Adult: 6.5mg daily (Zn2+ 100 micromol).
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  • Drugs used for Psoriasis and Eczema, Zinc Oxide
    Dosage form: Ointment
    Strength: 0.2
    Indications/Special comments: Protective coating for mild skin irritations and abrasions, soothing and protective ointment to promote healing of chapped skin and diaper rash.
    Dosage Administration: Infants, children and adults: Apply topically to affected area several times daily.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Zuclopenthixol Deconate
    Dosage form: Injection
    Strength: 100 mg/ml, 200mg/ ml
    Indications/Special comments: Maintenance in schizophrenia and paranoid psychoses
    Dosage Administration: By deep intramuscular injection. Adult: Test dose 100mg, dose to be administered into the upper outer buttock or lateral thigh, followed by 200 – 500mg after at least 7 days, then 200 – 500mg every 1 – 4 weeks, adjusted according to response, higher doses of more than 500mg can be used; do not exceed 600mg weekly. Elderly: A quarter to half usual starting dose to be used.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Zuclopenthixol Acetate
    Dosage form: Injection
    Strength: 50mg/ml
    Indications/Special comments: Short-term management of acute psychosis, mania, and exacerbation of chronic psychosis
    Dosage Administration: By deep intramuscular injection. Adult: 50 – 150mg, then 50 –150mg after 2 – 3 days if required, (1 additional dose may be needed 1 – 2 days after the first injection); maximum cumulative dose 400mg in 2 weeks and maximum 4 injections; maximum duration of treatment 2 weeks—if maintenance treatment necessary change to an oral antipsychotic 2 – 3 days after last injection, or to a longer acting antipsychotic depot injection given concomitantly with last injection of zuclopenthixol acetate; to be administered into the gluteal muscle or lateral thigh. Elderly: 50 – 100mg, then 50 – 100mg after 2 – 3 days if required, (1 additional dose may be needed 1 – 2 days after the first injection); maximum cumulative dose 400mg in 2 weeks and maximum 4 injections; maximum duration of treatment 2 weeks—if maintenance treatment necessary change to an oral antipsychotic 2 – 3 days after last injection, or to a longer acting antipsychotic depot injection given concomitantly with last injection of zuclopenthixol acetate; to be administered into the gluteal muscle or lateral thigh.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Zopiclone
    Dosage form: Tablet
    Strength: 3.75mg, 7.5mg
    Indications/Special comments: Insomnia (short-term use); Insomnia (short-term use) in patients with chronic pulmonary insufficiency
    Dosage Administration: Insomnia (short-term use): Adult: 7.5mg once daily for up to 4 weeks, dose to be taken at bedtime. Elderly: Initially 3.75mg once daily for up to 4 weeks, dose to be taken at bedtime, increased if necessary to 7.5mg daily. Insomnia (short-term use) in patients with chronic pulmonary insufficiency: Adult: Initially 3.75mg once daily for up to 4 weeks, dose to be taken at bedtime, increased if necessary to 7.5mg daily.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Zolpidem
    Dosage form: Tablet
    Strength: 10mg
    Indications/Special comments: Treatment of insomnia
    Dosage Administration: Adult: 10mg at bedtime. Hepatic impairment and the Elderly: 5mg
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Ziprasidone Mesylate
    Dosage form: Injection
    Strength: 20mg
    Indications/Special comments: Treatment of schizophrenia; treatment of acute manic or mixed episodes associated with bipolar disorder with or without psychosis; maintenance treatment of bipolar disorder as an adjunct to lithium or valproate; acute agitation in patients with schizophrenia.
    Dosage Administration: Acute agitation (schizophrenia): Adults: IM: 10mg every 2 hours or 20mg every 4 hours; maximum: 40mg daily; oral therapy should replace IM administration as soon as possible.
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  • Antivirals, Zidovudine + Lamivudine (Combivir)
    Dosage form: Tablet
    Strength: 300mg + 150mg
    Indications/Special comments: HIV infection; reduction of perinatal transmission of HIV; post-exposure prophylaxis; only in combination with other antiretrovirals.
    Dosage Administration: Adult and Child >12 years: Oral: one tablet twice daily
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  • Antivirals, Zidovudine (ZDV, AZT)
    Dosage form: Injection
    Strength: 20mg/ml
    Indications/Special comments: HIV infection; reduction of perinatal transmission of HIV; Postexposure prophylaxis. Usually in combination with other antiretrovirals.
    Dosage Administration: Adult: IV infusion: over 1 hour, 1 - 2mg/kg 4 hourly, in 5% glucose to give a zidovudine concentration 2 or 4mg/ml. The IV route is used only until oral therapy can be given. PMTCT: Neonates: IV: 1 - 5mg/kg 8 hourly; Premature infants IV: as for term infants.
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  • Analgesics, Zolmitriptan
    Dosage form: Tablet
    Strength: 2.5mg, 5mg
    Indications/Special comments: Treatment of acute migraine; Treatment of cluster headaches; Off label for menstrual migraines, prophylaxis 2.5mg 2 - 3 times daily starting 2 days before expected onset of menses and continue through 5 days after onset of menses (7 days total).
    Dosage Administration: Treatment of acute migraine: Adult: 2.5mg, followed by 2.5mg after at least 2 hours if required, dose to be taken only if migraine recurs, then increased if necessary to 5mg, dose to be taken only for subsequent attacks in patients not achieving satisfactory relief with 2.5mg dose; maximum 10mg per day. Dose adjustments due to interactions: Max. 5mg in 24 hours with concomitant cimetidine, fluvoxamine, moclobemide, or quinolone antibiotics.
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