• Cardiovascular Drugs, Valsartan
    Dosage form: Tablet
    Strength: 40mg, 80mg, 160mg, 320mg
    Indications/Special comments: Treatment of hypertension alone or in combination with other antihypertensives. Treatment of heart failure.
    Dosage Administration: Adult: Initial: 80 mg once daily; maximum recommended dose: 320mg/day. Heart failure: initial: 40mg twice daily; titrate dose to 80 - 160mg twice daily, maximum daily dose 320mg.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Valproic Acid
    Dosage form: Syrup
    Strength: 250mg/5ml
    Indications/Special comments: Treatment of manic episodes associated with bipolar disorder.
    Dosage Administration: Treatment of manic episodes associated with bipolar disorder: By mouth: Adult: Initially 750mg daily in 2 – 3 divided doses, then increased to 1 – 2g daily, adjusted according to response, doses greater than 45mg/kg daily require careful monitoring.
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  • Anxiolytics, Sedatives, Hypnotics and Antipsychotics, Valproic Acid
    Dosage form: Capsule
    Strength: 250mg
    Indications/Special comments: Treatment of manic episodes associated with bipolar disorder.
    Dosage Administration: Treatment of manic episodes associated with bipolar disorder: By mouth: Adult: Initially 750mg daily in 2 – 3 divided doses, then increased to 1 – 2g daily, adjusted according to response, doses greater than 45mg/kg daily require careful monitoring.
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  • Antivirals, Valacyclovir
    Dosage form: Tablet
    Strength: 500mg, 1g
    Indications/Special comments: Treatment of herpes zoster and of herpes simplex infections of the skin and mucous membranes including initial and recurrent genital herpes.
    Dosage Administration: Herpes zoster: 1g 3 times daily for 7 days. Herpes simplex, first episode, 500mg twice daily for 5 days (up to 10 days if severe); recurrent infection, 500mg twice daily for 5 days. Child: not recommended.
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  • Antineoplastics and Related Agents, Vinorelbine
    Dosage form: Injection
    Strength: 10mg/ml; 50mg/5ml
    Indications/Special comments: Advanced breast cancer. Advanced non-small cell lung cancer.
    Dosage Administration: In combination with Cisplatin 100mg/m2: The recommended dose of Vinorelbine is 25mg/m2 administered as an intravenous injection or infusion over 6 to 10 minutes on days 1, 8, 15 and 21 of a 28 day cycle in combination with cisplatin 100mg/m2 on day 1 only of each 28 day cycle. In combination with Cisplatin 120mg/m²: The recommended dose of Vinorelbine is 30mg/m² administered as an intravenous injection or infusion over 6 to 10 minutes once a week in combination with cisplatin 120mg/m² on days 1 and 29, then every 6 weeks. Single-Agent: The recommended dose of Vinorelbine is 30mg/m² administered intravenously over 6 to 10 minutes once a week.
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  • Antineoplastics and Related Agents, Vincristine Sulfate
    Dosage form: Powder for Injection
    Strength: 1mg
    Indications/Special comments: Acute lymphoblastic leukemia; neuroblastoma; Wilms tumor; Hodgkin and non-Hodgkin lymphomas; rhabdomyosarcoma; Ewing sarcoma; mycosis fungoides.
    Dosage Administration: (Refer to individual protocols): Adult: 0.4 - 1.4mg/m2, may repeat every week or 0.4 - 0.5mg/day continuous infusion for 4 days every 4 weeks or 0.25 - 0.5mg/m2/day for 5 days every week.
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  • Antineoplastics and Related Agents, Vinblastine Sulfate
    Dosage form: Powder for Injection
    Strength: 10mg
    Indications/Special comments: Treatment of Hodgkin’s and non-Hodgkin’s lymphoma; advanced testicular carcinoma, breast carcinoma; palliative treatment of Kaposi’s sarcoma, trophoblastic tumors.
    Dosage Administration: (Refer to individual protocols): Adult and Child: IV: 4 - 20mg/m2 (0.1 - 0.5mg/kg) every 7 - 10 days or 5 day continuous infusion of 1.5 - 2mg/m2/day or 0.1 - 0.5mg/kg/week.
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  • Antidepressants, Venlafaxine Hydrochloride
    Dosage form: Tablet
    Strength: 37.5mg
    Indications/Special comments: Major depression, generalized anxiety disorder, social anxiety disorder.
    Dosage Administration: Adult: Initially 75mg daily in 2 divided doses, then increased if necessary up to 375mg daily, dose to be increased if necessary at intervals of at least 2 weeks, faster dose titration may be necessary in some patients; maximum 375mg per day.
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  • Antidepressants, Venlafaxine Hydrochloride
    Dosage form: Capsule ER
    Strength: 37.5mg, 75mg, 150mg
    Indications/Special comments: Major depression, generalized anxiety disorder, social anxiety disorder.
    Dosage Administration: Adult: Initially 75mg once daily, increased if necessary up to 375mg once daily, dose to be increased if necessary at intervals of at least 2 weeks, faster dose titration may be necessary in some patients; maximum 375mg per day. Generalized anxiety disorder: Adult: 75mg once daily, increased if necessary up to 225mg once daily, dose to be increased at intervals of at least 2 weeks; maximum 225mg per day. Social anxiety disorder: Adult: 75mg once daily, there is no evidence of greater efficacy at higher doses, increased if necessary up to 225mg once daily, dose to be increased if necessary at intervals of at least 2 weeks; maximum 225mg per day.
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  • Antibacterials, Vancomycin
    Dosage form: Injection
    Strength: 500mg
    Indications/Special comments: Generally reserved for the treatment of infections due to cloxacillin-resistant staphylococci and enterococci; also as an alternative agent for prophylaxis and treatment of endocarditis in penicillin allergic patients.
    Dosage Administration: IV infusion: Adult: over at least 1 hour, 500mg 6 hourly or 1g 12 hourly. Child: over at least 1 hour, 10mg/kg 6 hourly or 20mg/kg 12 hourly. Neonates: under 1 week old, initially 15mg/kg followed by 10mg/kg 12 hourly; 1 week - 1 month old, 15mg/kg followed by 10mg/kg 8 hourly.
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