• Vitamins and Minerals, Vitamin B Complex
    Dosage form: Injection
    Strength: n/a
    Indications/Special comments: In disorders requiring parenteral administration of vitamins, i.e. pre- and post-operative treatment, when requirements are increased as in fever, severe burns, increased metabolism, pregnancy, gastrointestinal disorders interfering with intake or absorption of vitamins, prolonged or wasting diseases, alcoholism and where other deficiencies exist.
    Dosage Administration: Usually 0.25 to 2mL by intramuscular or slow intravenous injection. High concentrations given intravenously may be diluted using parenteral infusion solutions.
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  • Vitamins and Minerals, Vitamin A
    Dosage form: Injection
    Strength: 50,000 IU/ml
    Indications/Special comments: For prevention or treatment of vitamin A deficiency states, causing keratomalacia, xerophthalmia and nyctalopia (night blindness). This may occur as a result of inadequate nutrition or intestinal malabsorption.
    Dosage Administration: Adult: Deficiency: IM, Intravenous infusion, as a part of total parenteral nutrition solution, the specific amount determined by individual patient need. - IM: 15,000 to 30,000 RE (50,000 - 100,000 units) a day for three days, followed by 15,000 RE (50,000 units) a day for two weeks. Child: Deficiency: Infants less than 1year: IM: 1500 - 3000 RE (500 - 10,000 units) a day for ten days; In severe deficiency: IM: 2250 to 4500 RE (7500 to 15,000 units) a day for ten days. Children 1 - 8 years of age: IM: 1500 - 4500 RE (5000 - 15,000 units) a day for ten days; In severe deficiency: IM: 5250 to 10,500 RE (17,500 - 35,000 units) a day for ten days.
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  • Neuromuscular Blockers, Vecuronium Bromide
    Dosage form: Powder for Injection
    Strength: 10mg
    Indications/Special comments: Muscle relaxant during surgery.
    Dosage Administration: IV: Intubation: Adult and Child over 5 months: 80 - 100mcg/kg; maintenance of relaxation 20 - 30mcg/kg. Child under 4 months: initially 10 - 20mcg/kg, followed by increments according to response. IV infusion: Adult: initial bolus 40 - 100mcg/kg then 0.8 - 1.4mcg/kg/minute.
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  • Insulin and Oral Antidiabetic, Vildagliptin
    Dosage form: Tablet
    Strength: 50mg
    Indications/Special comments: Type 2 diabetes mellitus as monotherapy (if metformin inappropriate). Type 2 diabetes mellitus in combination with metformin or pioglitazone (when treatment with either metformin or pioglitazone fails to achieve adequate glycaemic control). Type 2 diabetes mellitus in combination with both metformin and a sulfonylurea (when dual therapy with these drugs fails to achieve adequate glycaemic control). Type 2 diabetes mellitus in combination with insulin (with or without metformin) when a stable dose of insulin has not provided adequate glycaemic control. Type 2 diabetes mellitus in combination with sulfonylurea (if metformin inappropriate).
    Dosage Administration: Type 2 diabetes mellitus in combination with sulfonylurea (if metformin inappropriate): By mouth. Adult: 50mg daily, dose to be taken in the morning. As monotherapy or other combinations: Adult: 50mg twice daily.
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  • Hormonal Preparations, Vasopressin
    Dosage form: Injection
    Strength: 20 units/ml
    Indications/Special comments: Treatment of diabetes insipidus, prevention and treatment of postoperative abdominal distention.
    Dosage Administration: Diabetes insipidus: SC or I.M: Adult: 5 - 10 units 2 - 4 times/day as needed. Child: 2.5 - 10 units 2 - 4 times/day as needed. Abdominal distention: Adult: I.M: 5 units stat, 10 units every 3 - 4 hours.
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  • Cardiovascular Drugs, Verapamil Hydrochloride
    Dosage form: Tablet
    Strength: 40mg, 80mg, 120mg, 240mg
    Indications/Special comments: Angina, paroxysmal supraventricular arrhythmias, atrial fibrillation and hypertension.
    Dosage Administration: Adult: Arrhythmias: Oral: 80 - 120mg 3 times daily (up to a total daily dose of 480mg); doses should be individualized. During chronic therapy, twice daily dosage should be adequate.
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  • Cardiovascular Drugs, Verapamil Hydrochloride
    Dosage form: Injection
    Strength: 2.5mg/ml
    Indications/Special comments: Angina, paroxysmal supraventricular arrhythmias, atrial fibrillation and hypertension.
    Dosage Administration: IV: initially 5mg, followed by 5 - 10mg after 10 minutes if needed; IV infusion, initial rates 0.0001 - 0.005mg/kg/minute, increase as required. Child: IV: < 1year, 0.1 - 0.2mg/kg; 1 - 15 years, 0.1 - 0.3mg/kg (maximum 5mg). May be repeated once after 30 minutes if the response is inadequate.
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  • Cardiovascular Drugs, Verapamil Hydrochloride
    Dosage form: Capsule ER
    Strength: 120mg, 180mg, 240mg
    Indications/Special comments: Angina, paroxysmal supraventricular arrhythmias, atrial fibrillation and hypertension.
    Dosage Administration: Essential Hypertension: The dose of verapamil hydrochloride extended-release capsules should be individualized by titration. The usual daily dose of extended-release verapamil hydrochloride capsules in clinical trials has been 240 mg given by mouth once daily in the morning. However, initial doses of 120 mg a day may be warranted in patients who may have an increased response to verapamil (e.g., elderly, small people, etc.). Upward titration should be based on therapeutic efficacy and safety evaluated approximately 24 hours after dosing. The antihypertensive effects of verapamil hydrochloride extended-release capsules are evident within the first week of therapy. If adequate response is not obtained with 120 mg of verapamil hydrochloride extended-release capsules, the dose may be titrated upward in the following manner: 180 mg in the morning, 240 mg in the morning, 360 mg in the morning, 480 mg in the morning. Verapamil extended-release capsules are for once a day administration. When switching from immediate-release verapamil to verapamil hydrochloride extended-release capsules, the same total daily dose of verapamil hydrochloride extended-release capsules can be used. As with immediate-release verapamil, dosages of verapamil hydrochloride extended-release capsules should be individualized and titration may be needed in some patients.
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  • Cardiovascular Drugs, Valsartan + Hydrochlorothiazide
    Dosage form: Tablet
    Strength: 80mg + 12.5mg; 160mg + 12.5mg; 160mg + 25mg; 320mg + 12.5mg; 320mg + 25mg
    Indications/Special comments: Hypertension not adequately controlled by valsartan alone.
    Dosage Administration: Initial dose: 1 tablet (12.5 - 160mg) orally once a day. Maintenance dose: Titrate as necessary (every 1 to 2 weeks) up to a maximum of 25mg - 320mg orally once a day.
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  • Cardiovascular Drugs, Valsartan + Amlodipine + Hydrochlorothiazide
    Dosage form: Tablet
    Strength: 160mg + 10mg + 12.5mg; 160mg + 5mg + 12.5mg; 160mg + 5mg + 25mg; 320mg +10mg + 25mg
    Indications/Special comments: Amlodipine, valsartan and hydrochlorothiazide tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
    Dosage Administration: Dose once-daily. The dosage may be increased after 2 weeks of therapy. The full blood pressure lowering effect was achieved 2 weeks after being on the maximal dose of amlodipine, valsartan and hydrochlorothiazide tablets. The maximum recommended dose of amlodipine, valsartan and hydrochlorothiazide tablets is 10/320/25mg. Add-on / Switch Therapy: Amlodipine, valsartan and hydrochlorothiazide tablets may be used for patients not adequately controlled on any 2 of the following antihypertensive classes: calcium channel blockers, angiotensin receptor blockers, and diuretics. A patient who experiences dose-limiting adverse reactions to an individual component while on any dual combination of the components of amlodipine, valsartan and hydrochlorothiazide tablets may be switched to amlodipine, valsartan and hydrochlorothiazide tablets containing a lower dose of that component to achieve similar blood pressure reductions.
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