• Anti-inflammatory Agents, Prednisone
    Dosage form: Tablet
    Strength: 5mg, 20mg
    Indications/Special comments: Treatment of a variety of diseases including: endocrine disorders, rheumatic disorders (adjunct), collagen diseases, dermatologic diseases, allergic states, ophthalmic diseases, respiratory diseases, haematologic disorders, neoplastic diseases, oedematous states, gastrointestinal diseasesMiscellaneous: Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy; trichinosis with neurologic or myocardial involvement.
    Dosage Administration: Adult: 10 – 20mg daily, adjusted according to response, dose to be take at bedtime. Gastric irritation may be reduced if taken before, during, or immediately after meals or with food or milk. Please see product leaflet.
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  • Anti-inflammatory Agents, Prednisone
    Dosage form: Solution
    Strength: 5mg/ml
    Indications/Special comments: Treatment of a variety of diseases including: endocrine disorders, rheumatic disorders (adjunct), collagen diseases, dermatologic diseases, allergic states, ophthalmic diseases, respiratory diseases, haematologic disorders, neoplastic diseases, oedematous states, gastrointestinal diseases.Miscellaneous: Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy; trichinosis with neurologic or myocardial involvement.
    Dosage Administration: Adult: 10 – 20mg daily, adjusted according to response, dose to be take at bedtime. Gastric irritation may be reduced if taken before, during, or immediately after meals or with food or milk. Please see product leaflet.
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  • Antigout, Probenecid
    Dosage form: Tablet
    Strength: 500mg
    Indications/Special comments: Long-term management of hyperuricemia associated with chronic gout. Note: It is not effective in the treatment of acute gout attacks and does not eliminate the need to use colchicine or non-steroidal anti-inflammatory drugs to relieve an attack.
    Dosage Administration: Adult: Antigout: Oral: Initial - 250mg two times a day for one week. Maintenance - 500mg two times a day. Child: dosage has not been established.
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  • Antiglaucoma Agents, Pilocarpine Nitrate
    Dosage form: Eye Drop
    Strength: 1%, 2%, 4%
    Indications/Special comments: Chronic open-angle glaucoma; ocular hypertension; emergency treatment of acute angle-closure glaucoma; to antagonize effects of mydriasis and cycloplegia following surgery or ophthalmoscopic examination
    Dosage Administration: Adult: Chronic open-angle glaucoma: by instillation into the eye, 1 drop (2% or 4%) up to 4 times daily. Acute angle-closure glaucoma before surgery: by instillation into the eye, 1 drop (2%) every 10 minutes for 30 - 60 minutes, then 1 drop every 1 - 3 hours until intraocular pressure subsides.
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  • Antidotes and other substances used in poisoning, Protamine Sulphate
    Dosage form: Injection
    Strength: 10mg/ml
    Indications/Special comments: Treatment of heparin overdosage.
    Dosage Administration: Protamine sulphate usually is administered by very slow IV injection over 10 minutes. No more than 50mg of the drug should be administered in any 10 minute period. See table below: Heparin route Time elapsed since heparin given Protamine Sulfate Per 100u heparin IV <15 minutes 1mg; IV 30 -60 minutes 0.5 - 0.75mg; IV > 2 hours 0.25 - 0.375mg; SC _ 1mg
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  • Antidotes and other substances used in poisoning, Phytomenadione (Vitamin K1)
    Dosage form: Injection
    Strength: 1mg/ml, 10mg/ml in 1ml ampoule.
    Indications/Special comments: Overdose of warfarin and related agents used in rodent poisons
    Dosage Administration: Dose and administration: Adult: IM: 10mg. Child: IM: 1 - 5mg. With severe toxicity, vitamin K1 may be given I.V.
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  • Antidotes and other substances used in poisoning, Physostigmine Salicylate
    Dosage form: Injection
    Strength: 1mg/ml
    Indications/Special comments: Reverse toxic CNS effects caused by anticholinergic drugs
    Dosage Administration: Adult: IM, IV, SC: 0.5 - 2mg to start, repeat every 20 minutes until response occurs or adverse effect occurs. Repeat 1 - 4mg every 30 - 60 min as life - threatening signs.Child: IV: 0.01 - 0.03mg/kg/dose (maximum: 0.5mg/min); may repeat after 5 - 10 minutes to a maximum total dose of 2mg.
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  • Antidepressants, Phenelzine Sulphate
    Dosage form: Tablet
    Strength: 15 mg
    Indications/Special comments: Depressive illness in patients clinically characterized as atypical, nonendogenous, or neurotic
    Dosage Administration: Depression. Adult: initial dose 15mg 3 times daily early phase increase rapidly as tolerated to 60 to 90mg/day (may take 4 weeks of 60mg/ day before clinical response. Maintenance: After maximum benefit obtained slowly reduce dose over several weeks dose may be as low as 15mg/day or every other day. Elderly: initially lower end of dosing range ie. 7.5mg increase of 7.5mg every 4 to 8 days as tolerated to achieve theraputic dose of 22.5 - 60mg/day in elderly.
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  • Antidepressants, Paroxetine
    Dosage form: Tablet (CR)
    Strength: 12.5mg, 25mg
    Indications/Special comments: Major depression; social anxiety disorder; post-traumatic stress disorder; generalised anxiety disorder; obsessive-compulsive disorder; panic disorder.
    Dosage Administration: CR formulation (MDD) 25mg daily increase if needed by 12.5mg/day at least a 1 week interval, max dose 62.5mg/day. Panic disorder: Oral: Adult: Initially 10mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually, increased to 40mg daily, no evidence of greater efficacy at higher doses; maximum 60mg per day. Elderly: Initially 10mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually; maximum 40mg per day. CR formulation - 12.5mg once daily increase if needed by 12.5mg/day at intervals of at least 1 week, max dose 7 mg/day. Social anxiety disorder: CR formulation- 12.5mg once daily increase if needed by 12.5mg/day at intervals of at least 1 week, max dose 37.5mg/day.
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  • Antidepressants, Paroxetine
    Dosage form: Tablet
    Strength: 10mg, 20mg
    Indications/Special comments: Major depression; social anxiety disorder; post-traumatic stress disorder; generalised anxiety disorder; obsessive-compulsive disorder; panic disorder.
    Dosage Administration: Major depression, Social anxiety disorder, Post-traumatic stress disorder, Generalised anxiety disorder: Oral: Adult: 20mg daily, dose to be taken in the morning, no evidence of greater efficacy at higher doses; maximum 50mg per day. Elderly: 20mg daily, dose to be taken in the morning, no evidence of greater efficacy at higher doses; maximum 40mg per day. Obsessive-compulsive disorder: Oral: Adult: Initially, 20mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually, increased to 40mg daily, no evidence of greater efficacy at higher doses; maximum 60mg per day. Elderly: Initially 20mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually; maximum 40mg per day. Panic disorder: Oral: Adult: Initially 10mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually, increased to 40mg daily, no evidence of greater efficacy at higher doses; maximum 60mg per day. Elderly: Initially 10mg daily, dose to be taken in the morning, increased in steps of 10mg, dose to be increased gradually; maximum 40mg per day.
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