• Thyroid Hormones and Antithyroid Agents, Liothyronine
    Dosage form: Tablet
    Strength: 5mcg
    Indications/Special comments: Treatment of hypothyroidism
    Dosage Administration: By mouth: Adult: Initially 10 – 20 micrograms daily; increased to 60 micrograms daily in 2 – 3 divided doses, dose should be increased gradually, smaller initial doses given for the elderly
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  • Thyroid Hormones and Antithyroid Agents, Levothyroxine Sodium
    Dosage form: Tablet
    Strength: 100mcg, 50mcg
    Indications/Special comments: Treatment of hypothyroidism
    Dosage Administration: Manufacturer recommends administering total daily dosage usually in 3 equally divided doses at approximately 8-hour intervals. Paediatric Patients: Graves’ Disease with Hyperthyroidism or Toxic Multinodular Goiter: Oral: initially, 0.4 mg/kg daily, usually given in 3 equally divided doses at approximately 8-hour intervals. Alternatively, some clinicians recommend usual dosage of 0.2 – 0.5mg/kg daily (range: 0.1 – 1mg/kg daily). These clinicians also suggest the following general dosages, calculated based on the patient's age and rounded to the nearest quarter-, half-, or whole-tablet dosage strengths: For infants: 1.25 mg daily; for children 1–5 years of age: 2.5 – 5 mg daily; for children 5 – 10 years of age: 5 – 10 mg daily; and for children 10 – 18 years of age: 10 – 20 mg daily. Patients with severe clinical or biochemical hyperthyroidism may receive dosages that are 50 – 100% higher than those usually recommended. Maintenance dosage: Approximately half of initial dosage or less. Preparation for Surgical Treatment: Oral: Initially, 0.4 mg/kg daily, usually given in 3 equally divided doses at approximately 8-hour intervals. Some clinicians recommend administering methimazole usually for 1 – 2 months to achieve euthyroidism in preparation for thyroidectomy in patients with Graves’ disease. Preparation for Radioactive Iodine Therapy: Oral: Initially, 0.4 mg/kg daily, usually given in 3 equally divided doses at approximately 8-hour intervals. Some clinicians recommend discontinuing methimazole 3 – 5 days before radioactive iodine therapy. Although some clinicians restart antithyroid drugs after radioactive iodine therapy, this practice is seldom required in children. Adults: Hyperthyroidism Graves’ Disease with Hyperthyroidism or Toxic Multinodular Goiter: Oral: Initially, 15mg daily for mild hyperthyroidism, 30 – 40mg daily for moderately severe hyperthyroidism, or 60mg daily for severe hyperthyroidism. Alternatively, some clinicians recommend an initial dosage of 10 – 20mg daily to restore euthyroidism. Considerable improvement or normal thyroid function generally achieved following 4 – 12 weeks of therapy, after which dosage may be decreased while maintaining normal thyroid function carefully adjust subsequent dosage according to patient’s tolerance and therapeutic response. Maintenance dosage: Manufacturer recommends 5 – 15mg daily. Alternatively, some clinicians recommend 5 – 10mg daily. Optimum duration of therapy not clearly established. However, some clinicians suggest continuing therapy for approximately 12 – 18 months, then taper or discontinue drug if TSH concentrations return to normal at that time. If patient remains hyperthyroid after completing a course of methimazole, consider treatment with radioactive iodine or thyroidectomy. However, may also consider long-term (>12 – 18 months) low-dose methimazole therapy in patients not in remission who prefer this pharmacologic approach. Preparation for Surgical Treatment: Oral: Initially, 15mg daily for mild hyperthyroidism, 30 – 40mg daily for moderately severe hyperthyroidism, or 60mg daily for severe hyperthyroidism. Discontinue methimazole at time of procedure. Preparation for Radioactive Iodine Therapy: Oral: Initially, 15mg daily for mild hyperthyroidism, 30 – 40mg daily for moderately severe hyperthyroidism, or 60mg daily for severe hyperthyroidism. Some clinicians recommend discontinuing methimazole 2 – 7 days before radioactive iodine; may restart methimazole 3 – 7 days after radioactive iodine, then generally taper over 4 – 6 weeks as thyroid function normalizes and radioactive iodine becomes effective. Thyrotoxic Crisis: Oral: Some clinicians recommend 60 – 80mg daily. See package insert for further information. Pregnancy: If used during pregnancy for management of hyperthyroidism, a sufficient, but not excessive, dosage is necessary; use lowest possible dosage. Thyroid dysfunction diminishes in many women as pregnancy proceeds; may be possible to reduce antithyroid dosage, and, in some patients, may discontinue antithyroid therapy 2 – 3 weeks before delivery. Special notes: May use a ß-adrenergic blocking agent (e.g., propranolol) concomitantly to manage peripheral signs and symptoms of hyperthyroidism, particularly cardiovascular effects (e.g., tachycardia).
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  • Respiratory Drugs, Levalbuterol
    Dosage form: Nebulizer Solution
    Strength: 0.32mg/3ml, 0.63mg/3ml, 1.25mg/3ml
    Indications/Special comments: Levalbuterol inhalation solution, USP is indicated for the treatment or prevention of bronchospasm in adults, adolescents, and children 6 years of age and older with reversible obstructive airway disease.
    Dosage Administration: Adults and Adolescents = 12 Years: The recommended starting dosage is 0.63mg administered 3 times a day, every 6 to 8 hours, by nebulization.Patients 12 years of age and older with more severe asthma or patients who do not respond adequately to a dose of 0.63mg of Levalbuterol inhalation solution may benefit from a dosage of 1.25mg 3 times a day.
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  • Respiratory Drugs, Levalbuterol
    Dosage form: Inhalent
    Strength: 45mcg
    Indications/Special comments: Levalbuterol inhalation solution, USP is indicated for the treatment or prevention of bronchospasm in adults, adolescents, and children 6 years of age and older with reversible obstructive airway disease.
    Dosage Administration: Levalbuterol inhalation solution is for oral inhalation only. Administer by nebulization using with a standard jet nebulizer (with a face mask or mouthpiece) connected to an air compressor. Do not exceed recommended dose
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  • Ophthalmic Anti-infectives, Levofloxacin
    Dosage form: Eye Drop
    Strength: 0.005
    Indications/Special comments: Local treatment of eye infections
    Dosage Administration: Bacterial conjunctivitis/ Corneal ulcers: Child 1 – 17 years: Apply every 2 hours for first 2 days, to be applied maximum 8 times a day, then apply 4 times a day for 3 days. Adult: Apply every 2 hours for first 2 days, to be applied maximum 8 times a day, and then apply 4 times a day for 3 days.
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  • Obstetric and Gynaecological Medications, Lynestrenol
    Dosage form: Tablet
    Strength: 0.5mg
    Indications/Special comments: Prevention of pregnancy
    Dosage Administration: Take 1 tablet daily.
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  • Insulin and Oral Antidiabetic, Liraglutide
    Dosage form: Injection
    Strength: Pre-filled pen 6ml/ml in 3ml cartridge
    Indications/Special comments: Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, or both, in patients who have not achieved adequate glycaemic control with these drugs alone or in combination. Type 2 diabetes mellitus in combination with basal insulin or both metformin and pioglitazone when dual therapy with these drugs fails to achieve adequate glycaemic control.
    Dosage Administration: Adult: Initially, 0.6mg once daily for at least 1 week, then increased to 1.2mg once daily for at least 1 week, and then increased if necessary up to 1.8mg once daily. Dose adjustments due to interactions. Dose of concomitant insulin or sulfonylurea may need to be reduced.
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  • Insulin and Oral Antidiabetic, Linagliptin
    Dosage form: Tablet
    Strength: 5mg
    Indications/Special comments: Type 2 diabetes mellitus: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes (noninsulin dependent, NIDDM) as monotherapy or in combination with other antidiabetic agents.
    Dosage Administration: Oral: Adults: Type 2 diabetes: 5 mg once daily.when using with insulin and or insulin secretagogues a lower dose of these may be needed
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  • Hormonal Preparations, Lynestrenol
    Dosage form: Tablet
    Strength: 0.5mg
    Indications/Special comments: Treatment of endometriosis
    Dosage Administration: Take 1 tablet daily.
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  • Hormonal Preparations, Levonorgestrel (D-Norgestrel) + Ethinylestradiol
    Dosage form: Tablet
    Strength: 0.15+0.03mg
    Indications/Special comments: The prevention of pregnancy in women who elect to use this product as a method of contraception.
    Dosage Administration: One tablet daily for 21 consecutive days per menstrual cycle according to prescribed schedule. Tablets are then discontinued for 7 days (three weeks on, one week off).
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