Thiamine Hydrochloride (Vitamin B1)

Drug Class: Vitamins and Minerals
Dosage Form: Tablet
Strength: 100mg
Indications/Special comments: For prevention and treatment of thiamine deficiency states that may occur as a result of inadequate nutrition or intestinal malabsorption. It is used for temporary metabolic correction of genetic enzyme deficiency diseases such as subacute nercotizing encephalomyelopathy (SNE, Leigh’s disease), maple syrup urine disease (branched-chain aminoacidopathy), and lactic acidosis associated with pyruvate carboxylase deficiency and hyperalaninemia.
Dosage Administration: Adult: Nutritional supplement (Vitamin) Beriberi (initial in mild or maintenance following severe): 5 to 10mg three times a day (in a multivitamin preparation). Beriberi (critical illness): IM or slow IV: 5 - 100mg three times a day followed by maintenance oral administration. Treatment of deficiency: 1 - 10mg three times a day until improvement occurs, followed by recommended dietary allowance. Child: Nutritional supplement (Vitamin) Beriberi (mild): Infants: 10mg per day. Beriberi (critical illness): Treatment of deficiency: Oral: 10 to 50mg per day in divided doses. Dietary supplement: Infants: Oral: 300 to 500mcg (0.3 - 0.5mg) per day. Child: Oral: 500mcg (0.5mg) to 1mg per day.