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Phentolamine Mesylate

Drug Class: Cardiovascular Drugs
Dosage Form: Injection
Strength: 10mg/ml
Indications/Special comments: Hypertensive episodes due to phaeochromocytoma e.g. during surgery
Dosage Administration: Hypertensive episodes due to phaeochromocytoma e.g. during surgery. By intravenous injection: Adult 2 – 5mg, repeated if necessary. Diagnosis of phaeochromocytoma: Phentolamine blocking test. The test is most reliable in detecting pheochromocytoma in patients with sustained hypertension and least reliable in those with paroxysmal hypertension. False-positive tests may occur in patients with hypertension without pheochromocytoma. Children: IM: 3mg, IV: 1mg. Adults: IM or IV: 5mg.