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Bupivacaine

Drug Class: Anaesthetic, Local
Dosage Form: Injection
Strength: 0.25%, 0.5%, 0.75% (preservative free)
Indications/Special comments: The 0.5% solution is chiefly indicated for peripheral nerve blocks, eye blocks, spinal and epidural (including caudal) anaesthesia. Diluted solutions (0.25%) have been used for local infiltration. Bupivacaine is particularly useful for producing prolonged analgesia during labour, where the interval between doses is usually 2 - 3 hours.
Dosage Administration: Adult: Dosage depends on site of injection, procedure used, and the status of the patient: Not more than 2mg/kg (with or without adrenaline) should be administered in any 4 hour period, and in 24 hours the total amount should not exceed 400mg. Child: Local infiltration: 2mg/kg. Regional anaesthesia: 2.5mg/kg.